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Lortab combines a narcotic analgesic (painkiller) and cough reliever with a non-narcotic analgesic for the relief of moderate to moderately severe pain.

General Information on Dosing With Lortab

Considerations for people taking Lortab include the following:

  • The medication comes in tablet and elixir form. It is taken by mouth, typically every four to six hours as needed for pain.
  • It is best to take Lortab with food, as this may help reduce stomach upset. Most opioids, including the one in Lortab, cause stomach upset.
  • Lortab tablets can be broken in half if necessary.
  • Be careful not to exceed the maximum recommended daily dose, as this could lead to overdose symptoms or poisoning from the acetaminophen component, which can cause liver failure.
  • Lortab is either taken "as needed" or on a scheduled basis. "As needed" means you will only take a dose if you are experiencing pain (if you are not in pain, you will skip the dose), while "scheduled use" means you should take it on schedule, even if you are not in pain. Most healthcare providers prescribe Lortab on an "as needed" basis, rather than a scheduled basis.
  • For the medication to work properly, it must be taken as prescribed. Do not increase your dose without your healthcare provider's approval. Do not suddenly stop taking Lortab, especially if you have taken it regularly for more than several weeks.
  • If you are unsure about anything related to your Lortab dosage, please talk with your doctor, nurse, or pharmacist. Do not stop taking the drug without first discussing it with your healthcare provider.

Side Effects

The most frequently reported adverse reactions are light-headedness, dizziness, sedation, nausea and vomiting. These effects seem to be more prominent in ambulatory than in non-ambulatory patients, and some of these adverse reactions may be alleviated if the patient lies down.

Special warnings about Lortab

Use Lortab with caution if you have a severe liver or kidney disorder, an underactive thyroid gland, Addison's disease (a disease of the adrenal glands), an enlarged prostate, or urethral stricture (narrowing of the tube carrying urine from the bladder).

Older adults and those in a weakened condition should be careful using Lortab, since it contains a narcotic.

Narcotics such as Vicodin may interfere with the diagnosis and treatment of people with abdominal conditions.

Drug Interactions

Patients receiving narcotics, antihistamines, antipsychotics, antianxiety agents, or other CNS depressants (including alcohol) concomitantly with hydrocodone bitartrate and acetaminophen tablets may exhibit an additive CNS depression. When combined therapy is contemplated, the dose of one or both agents should be reduced.

The use of MAO inhibitors or tricyclic antidepressants with hydrocodone preparations may increase the effect of either the antidepressant or hydrocodone.

Storage

Store at 20 to 25?°C (68 to 77?°F).

Dispense in a tight, light-resistant container with a child-resistant closure.

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